What is MODY Diabetes?

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diabetesMost of us are aware that there are different types of diabetes. Type 1 and type 2 diabetes are the two major forms of this disease. But have you ever come across the term MODY diabetes? Well, it refers to Maturity Onset Diabetes of Young (MODY). It affects around 1 or 2 per cent of diabetics. A person can develop this form of the disease before he/she reaches the age of 25 and the symptoms can often go unrecognized.

A person may have a higher chance of inheriting this type of diabetes when compared to the other types of the disease and the reason for this is a stronger genetic risk factor. This type of diabetes can pass on from generation to generation. Insulin treatment is generally not required to treat MODY.

Why do people inherit MODY so easily?

MODY diabetes is primarily caused due to change in one particular gene. If one of the parents has MODY, there is a 50% chance that all the children will inherit this gene and develop MODY themselves.

Why is it important for you to know about the various types of MODY?

6 types of MODY diabetes have been identified and it is important to know and understand all that there is about this type of disease and its different forms. If a loved one, family member or a friend is affected by this condition, you can give advice about the progress of the disease, expected complications and the treatment options. You could also advice other members of the family about the possible risks of inheriting this disease.

What are the various types of MODY?

HNF1 alpha is the common MODY diabetes type. It is responsible for almost 70% of all MODY cases. As a person gets older, the production of insulin by the pancreas is reduced. MODY develops mostly during adolescence. People in their early twenties can also develop this condition.

The next type (2nd type) of MODY is Glucokinase. It occurs due to the malfunctioning of a gene that helps the body to recognize blood glucose levels. Glucokinase can be difficult to identify as the symptoms do not show up that quickly. It is normally detected during the regular and routine testing. Pregnant women having a family history of MODY should be screened for it.

Another form of diabetes MODY that is less common is HNF4 – alpha. HNF1 -beta is the other type of MODY and renal cysts are associated with it. NeuroD1, IPF1 and PDX1 are other rarer types of MODY.

What can you do to prevent complications?

Researchers have recently found that diabetes MODY can cause certain complications in people affected by it. Managing the disease is of primary importance in order to prevent complications,. You can seek expert opinion from a diabetes specialist and know more about ways to manage this condition.

Sometimes, people get confused and think that MODY and type 2 diabetes are the same as some of the symptoms for both these types are identical. There is no link between MODY and obesity. Typical MODY diabetics are not necessarily overweight.

If you are worried that you have MODY diabetes, consult a doctor or a specialist immediately. Early detection can help in better management of the condition.


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